朗读老师:章维昆明医院
翻译老师:司医院
History:A48-year-oldwomanpresentswithsubacuteweaknessthatisgreaterontherightthanleft,pronatordrift,dyspneaonexertion,hypoesthesiaofherfeet,anddysgeusia.
AnunenhancedCTscanwasperformed.Axialimageisshownbelow.
病史:一位48岁女性,表现为亚急性虚弱,右侧大于左侧,旋前肌漂移,用力时呼吸困难,足部感觉减退,以及味觉障碍。
进行平扫CT扫描。轴向图像如下所示。
MRimagesAbrainMRIscanwasperformed.Axialfluid-attenuatedinversion-recovery(FLAIR)andaxialT1-weightedpostcontrastimages,aswellasanaxialapparentdiffusioncoefficient(ADC)map,areshownbelow.Clicktoenlarge.
进行脑部核磁共振扫描。轴位液体衰减反演恢复(FLAIR)和轴位T1加权增强后图像以及轴位表观扩散系数(ADC)图如下所示
Findings
HeadCT:Therearemultipleareas,includingthetemporallobes,ofhypoattenuationinthewhitematterbilaterallyconsistentwithvasogenicedema.Thereismildmasseffectassociatedwithregionsofvasogenicedema.Thereismilddiffusesulcaleffacement.
结果
?头颅CT:双侧白质有多个区域(包括颞叶)低密度,与血管源性水肿一致。与血管源性水肿相关的区域有轻微的占位效应。轻度弥漫性脑沟消失。
HeadMRI:MRIshowsmultipleinfra-andsupratentoriallesionswithsurroundingvasogenicedema,andmanyofthemhaveanalternatingpatternofhypo-andhyperintensesignalonT2-weighted/FLAIRimaging--i.e.,theso-calledtargetpatternofenhancement.Thereisnoevidenceofrestricteddiffusionandnoevidenceofabnormalmeningealenhancement.
头部MRI:MRI显示多个幕下和幕上病变,周围有血管源性水肿,其中许多在T2加权/FLAIR成像上呈低信号和高信号交替模式,即所谓的增强后靶征。没有证据表明扩散受限,也没有证据表明脑膜异常强化。
Differentialdiagnosis
Neurotoxoplasmosis
Metastaticdisease
Bacterialinfectionwithabscess
Centralnervoussystemlymphoma
Diagnosis:Neurotoxoplasmosis
鉴别诊断
脑弓形虫感染
转移性疾病
细菌感染伴脓肿
中枢神经系统淋巴瘤
诊断:脑弓形虫感染
DiscussionNeurotoxoplasmosis
Pathophysiology
Toxoplasmagondiiisaparasitethatisusuallyasymptomaticinimmuno